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Article

Genetic polymorphisms and other risk factors associated with bisphosphonate induced osteonecrosis of the jaw.

International journal of oral and maxillofacial surgery - 1 Jun 2011

Katz J, Gong Y, Salmasinia D, Hou W, Burkley B, Ferreira P, Casanova O, Langaee T Y, Moreb J S

Abstract excerpt

Bisphosphonate induced osteonecrosis of the jaw (BONJ) is a complication in patients taking bisphosphonate (BP) that affects their quality of life and compliance. In this cohort study, patients with multiple myeloma (MM) on intravenous BP therapy were enrolled over 1 year. Demographic and clinical data and genotyping of 10 single nucleotide polymorphisms (SNPs) from seven candidate genes associated with drug or...

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Share to Bone Density Conservation Agents
Share to Collagen Type I, alpha 1 Chain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2C8

Share to Diphosphonates

Share to Injections, Intravenous

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Share to Receptor Activator of Nuclear Factor-kappa B

Source

Identifiers

PMID: 21396799
DOI: 10.1016/j.ijom.2011.02.002

Genes

MMP2

Provenance

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