Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between MTHFD1 polymorphisms and neural tube defect susceptibility.

Journal of the neurological sciences - 15 Jan 2015

Meng Jingjing, Han Lei, Zhuang Bo

Abstract excerpt

OBJECTIVES: Neural tube defect (NTD) is a common disease among neonates with multiplex symptom and complex origins, and the exact mechanism of NTD has not been definitely elucidated. Nevertheless, it is hypothesized that NTD risk can be prevented by periconceptional folic acid in folate metabolism. The methylenetetrahydrofolate dehydrogenase (MTHFD1) gene has been proved to play an important role in folate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Genetic Association Studies
Share to Infant, Newborn

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Infant, Newborn, Diseases

Share to Methylenetetrahydrofolate Dehydrogenase (NADP)

Share to Minor Histocompatibility Antigens

Share to Neural Tube Defects

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 25524527
DOI: 10.1016/j.jns.2014.12.001

Genes

MTHFD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between MTHFD1 polymorphisms and neural tube defect susceptibility.PMID 25524527Read ↗

Association between MTHFD1 G1958A polymorphism and neural tube defects susceptibility: a meta-analysis.Semantic proximity Read ↗

MTHFD1 polymorphism as maternal risk for neural tube defects: a meta-analysis.Semantic proximity Read ↗

Polymorphisms in MTHFD1 Gene and Susceptibility to Neural Tube Defects: A Case-Control Study in a Chinese Han Population with Relatively Low Folate Levels.Semantic proximity Read ↗

Correlation analysis of MTHFD1 gene polymorphisms and neural tube defects in Han population of Northern ChinaSemantic proximity Read ↗

Variants in MTHFR gene and neural tube defects susceptibility in China.Semantic proximity Read ↗

Association of the maternal MTHFR C677T polymorphism with susceptibility to neural tube defects in offsprings: evidence from 25 case-control studies.Semantic proximity Read ↗

Evaluation of a methylenetetrahydrofolate-dehydrogenase 1958G>A polymorphism for neural tube defect risk.Semantic proximity Read ↗

"Polymorphisms in folate metabolism genes as maternal risk factor for neural tube defects: an updated meta-analysis".Semantic proximity Read ↗

Genetic variants in the folate pathway and the risk of neural tube defects: a meta-analysis of the published literature.Semantic proximity Read ↗

Association of main folate metabolic pathway gene polymorphisms with neural tube defects in Han population of Northern China.Semantic proximity Read ↗

Investigations of single nucleotide polymorphisms in folate pathway genes in Chinese families with neural tube defects.Semantic proximity Read ↗

Analysis of MTR and MTRR Polymorphisms for Neural Tube Defects Risk Association.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.