Article
The ABCC2 c.-24C>T polymorphism increases the risk of resistance to antiepileptic drugs: A meta-analysis.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Mar 2017
Qian Long, Fang Shu, Yan Yuan-Liang, Zeng Shuang-Shuang, Xu Zhi-Jie, Gong Zhi-Cheng
Abstract excerpt
Several studies examined a possible link between multidrug resistance-associated protein 2 (ABCC2) gene variants and the risk of resistance to antiepileptic drugs (AEDs) in epilepsy, but the results were contradictory. In this study, a meta-analysis was conducted to assess the relevance of ABCC2 common variants (c.-24C>T, c.1249G>A, c.3972C>T) with the response risk of AEDs. We searched Embase, PubMed, the...
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