Back to search

Article

ABCC2 rs2273697, rs717620, rs3740066 Polymorphisms and Antiseizure Medication Resistance: A Systematic Review and Meta-Analysis

2026-02-04

Abstract excerpt

<title>Abstract</title> <p>Objective Genetic variations in the ABCC2 gene have been proposed to influence resistance to antiseizure medications, but published findings to date are inconsistent. We aimed to systematically assess the association of three ABCC2 polymorphisms, rs2273697 (c.1249G > A, p.Val417Ile), rs717620 (c.-24C > T, 5′UTR), and rs3740066 (c.3972C > T, p.Lys1324Lys), with drug-resistant epilepsy a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
00e88050-1c71-5ca7-bf29-2dc0ec0c461c
DOI
10.21203/rs.3.rs-8270204/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
ABCC2 rs2273697, rs717620, rs3740066 Polymorphisms and Antiseizure Medication Resistance: A Systematic Review and Meta-AnalysisDOI 10.21203/rs.3.rs-8270204/v1
The ABCC2 c.-24C>T polymorphism increases the risk of resistance to antiepileptic drugs: A meta-analysis.Semantic proximity
A systematic review and meta-analysis of the association of ABCC2/ABCG2 polymorphisms with antiepileptic drug responses in epileptic patients.Semantic proximity
A systematic review and meta-analysis of the role of ABCC2 variants on drug response in patients with epilepsy.Semantic proximity
The effects of ABCC2 G1249A polymorphism on the risk of resistance to antiepileptic drugs: a meta-analysis of the literature.Semantic proximity
ABCC2 polymorphisms and haplotype are associated with drug resistance in Chinese epileptic patients.Semantic proximity
ABCB1, ABCC2, SCN1A, SCN2A, GABRA1 gene polymorphisms and drug resistant epilepsy in the Chinese Han population.Semantic proximity
Association between the polymorphisms in the ATP-binding cassette genes ABCB1 and ABCC2 and the risk of drug-resistant epilepsy in a Chinese Han population.Semantic proximity
Association of ABCB1 polymorphisms with carbamazepine metabolism and resistance in epilepsy: A meta-analysis.Semantic proximity
Association between ABCB1 C3435T polymorphism and antiepileptic drug resistance in epilepsy: An updated meta-analysis based on 62 studies.Semantic proximity
Lack of association between ABCC2 gene variants and treatment response in epilepsy.Semantic proximity
ABCC2 rs2273697 and rs3740066 polymorphisms and resistance to antiepileptic drugs in Asia Pacific epilepsy cohorts.Semantic proximity
Drug Resistance in Epilepsy: Clinical Impact, Potential Mechanisms, and New Innovative Treatment OptionsSemantic proximity
Select a neighboring publication to make it the new centre.