Article
A systematic review and meta-analysis of the role of ABCC2 variants on drug response in patients with epilepsy.
Epilepsia - 1 May 2013
Grover Sandeep, Kukreti Ritushree
Abstract excerpt
PURPOSE: Increasing evidence suggests that genetic variants from ABCC2 transporter may be associated with an altered response to antiepileptic drugs (AEDs). However, the variability in the selective inclusion of genetic variants in different studies makes delineation of the causal variant/s difficult. Furthermore, the differences in the frequency distribution and linkage disequilibrium (LD) pattern among genetic...
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