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Article

Next-generation sequencing in advanced Chinese melanoma reveals therapeutic targets and prognostic biomarkers for immunotherapy.

Scientific reports - 10 Jun 2022

Huang Fuxue, Li Jingjing, Wen Xizhi, Zhu Baoyan, Liu Wei, Wang Jiuhong, Jiang Hang, Ding Ya, Li Dandan, Zhang Xiaoshi

Abstract excerpt

Limited studies have interrogated the genomic landscape of Chinese melanoma in which acral and mucosal melanoma are the mainstay. In this study, we carried out a retrospective analysis on 81 Chinese melanoma patients (15 acral, 25 mucosal and 41 cutaneous melanoma). With the identification of 1114 mutations spanning 248 genes, we summarized that the mutation spectrum varied significantly by subtypes. Acral...

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Identifiers

PMID: 35688842
DOI: 10.1038/s41598-022-13391-y
PMCID: PMC9187737

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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