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Article

HtrA2/Omi is involved in 6-OHDA-induced endoplasmic reticulum stress in SH-SY5Y cells.

Journal of molecular neuroscience : MN - 1 May 2012

Luo Feifei, Wei Lei, Sun Congcong, Chen Xiaowu, Wang Tan, Li Yi, Liu Zhuolin, Chen Zhibin, Xu Pingyi

Abstract excerpt

Endoplasmic reticulum (ER) stress has been shown to be associated with the pathogenesis of neurodegenerative disorders including Parkinson's disease (PD). HtrA2/Omi, from its participation in protein quality control, is involved in ER stress. However, little is known about the relationship between HtrA2/Omi and ER stress in PD. Here, we explored the association of HtrA2/Omi and ER stress in a cell model of PD and...

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PMID: 22246992
DOI: 10.1007/s12031-011-9694-0

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HtrA2/Omi is involved in 6-OHDA-induced endoplasmic reticulum stress in SH-SY5Y cells.PMID 22246992Read ↗

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Loss of HtrA2/Omi activity in non-neuronal tissues of adult mice causes premature aging.Semantic proximity Read ↗

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