Article
6-Hydroxydopamine Induce Neurodegeneration In Terminally Differentiated SH-SY5Y Neuroblastoma Cells Via Enrichment Of The Nucleosomal Degradation Pathway: A Global Proteomic Approach
2021-04-30
Abstract excerpt
<title>Abstract</title> <p>The SH-SY5Y human neuroblastoma cells have been used for decades as an <italic>in vitro</italic> cell model of dopaminergic neurons to explore the underlying science of cellular and molecular mechanisms of neurodegeneration in Parkinson’s disease (PD). However, data revealing the protein expression changes in 6-OHDA induced cytotoxicity in differentiated SH-SY5Y cells remain void. There...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 6545dd2a-5015-596a-8961-09308c8c0f57
- DOI
- 10.21203/rs.3.rs-441687/v1
