Article
Genetic variations of Omi/HTRA2 in Chinese patients with Parkinson's disease.
Brain research - 18 Apr 2011
Wang Chun-Yu, Xu Qian, Weng Ling, Zhang Qiang, Zhang Hai-Nan, Guo Ji-Feng, Tan Li-Ming, Tang Jian-Guang, Yan Xin-Xiang, Tang Bei-Sha
Abstract excerpt
Parkinson's disease (PD) is the second most common neurodegenerative disorder, with approximately 5-10% of PD cases being linked to genetic factors. The Htra serine peptidase 2 (HTRA2) gene, also known as Omi, was found to be associated with PD in a cohort of German PD patients. However, subsequent studies have indicated that some variants of Omi/HTRA2 may not be related to PD. In order to investigate whether the...
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