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Article

Apoptosis inducer NGFI-B is degraded by the proteasome and stabilized by treatment with EGF.

Biochemical and biophysical research communications - 27 Jan 2012

Strøm Bjørn O, Paulsen Ragnhild E

Abstract excerpt

NGFI-B is a nuclear receptor and immediate early gene that is upregulated in many different tumour cell lines. As it is involved in cell death and survival, it has been suggested as a target for anti-cancer drugs. The protein level of NGFI-B is important for its functions and may be regulated through induction or stabilization. NGFI-B protein stability was studied using the protein synthesis inhibitor...

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Source

Identifiers

PMID: 22234305
DOI: 10.1016/j.bbrc.2011.12.132

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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