Article

Processing of Human Nerve Growth Factor β Proprotein in the Plant Cell Apoplast

2021-01-05

Abstract excerpt

The Human HNGF-β gene encodes a pre-pro-NGF-β precursor protein. The signal peptide is cleaved off in the endoplasmic reticulum and the resulting pro-protein is processed in the trans-Golgi network by the Furin enzyme.The processing of the proproteins in the plant cells is not clearly defined. In the present study, various changes were applied to the HNGF-β gene sequence to increase its expression in the plant cel...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f088f589-4e9a-5255-92c9-490b28293d5d
DOI: 10.21203/rs.3.rs-136984/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Processing of Human Nerve Growth Factor β Proprotein in the Plant Cell ApoplastDOI 10.21203/rs.3.rs-136984/v1Read

Construction and preliminary characterization of human recombinant proNGF-A variant.Semantic proximity Read

Proteolytic processing of proNGF is necessary for mature NGF regulated secretion from neurons.Semantic proximity Read

Expression of active human epidermal growth factor (hEGF) in tobacco plants by integrative and non-integrative systemsSemantic proximity Read

Plant-derived recombinant human insulin-like growth factor precursor prohormone IGF-1B caused differentiation of human neuroblastoma cell lines SH-SY5YSemantic proximity Read

Production of highly pure human glycosylated GDNF in a mammalian cell line.Semantic proximity Read

Construction of a mutated pro-nerve growth factor resistant to degradation and suitable for biophysical and cellular utilization.Semantic proximity Read

Stable and efficient expression of brain-derived neurotrophic factor in tobacco chloroplastsSemantic proximity Read

Neuronal differentiation of neural progenitor cells by intracellular delivery of synthetic oligopeptide derived from Von Hippel-Lindau protein.Semantic proximity Read

Nerve growth factor (NGF) influences differentiation and proliferation of myogenic cells in vitro via TrKASemantic proximity Read

Production of biologically active human basic Fibroblast Growth Factor (hFGFb) using <i>Nicotiana tabacum</i> transplastomic plantsSemantic proximity Read

Human ProNGF: biological effects and binding profiles at TrkA, P75NTR and sortilin.Semantic proximity Read

Processing of the 2S storage protein pronapin in Brassica napus and in transformed tobacco.Semantic proximity Read