Article
Involvement of mature tau isoforms in the stabilization of neurites in PC12 cells.
Journal of neuroscience research - 1 Sept 1991
Hanemaaijer R, Ginzburg I
Abstract excerpt
Tau microtubule-associated proteins are believed to play a role in regulation of the growth of neuronal processes. In order to study the function of tau protein in vivo, we examined the inhibition of tau expression in PC12 cells by exposing the cells to tau antisense oligodeoxynucleotides. A spec...
Topics
- Animals
- Base Sequence
- Cell Differentiation
- Colchicine
- Fluorescent Antibody Technique
- Genetic Variation
- Molecular Sequence Data
- Nerve Growth Factors
- Neurites
- Oligonucleotides, Antisense
- PC12 Cells
- Tubulin
- tau Proteins