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Article

Mutations of the core promoter and response to interferon treatment in chronic replicative hepatitis B.

Hepatology (Baltimore, Md.) - 1 Mar 2000

Erhardt A, Reineke U, Blondin D, Gerlich W H, Adams O, Heintges T, Niederau C, Häussinger D

Abstract excerpt

In chronic replicative hepatitis B the significance of mutations in the basic core promoter (BCP), core upstream regulatory sequences (CURS) and negative regulatory element (NRE) for response to interferon (IFN) is unknown. A sequence analysis of the NRE, CURS, BCP, and precore region was performed from sera of 96 patients with chronic replicative hepatitis B (64 hepatitis B e antigen [HBeAg]-positive patients...

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Identifiers

PMID: 10706563
DOI: 10.1002/hep.510310323

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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