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Article

Human hepatitis B virus enhancer 1 is responsive to human interleukin-6.

Journal of medical virology - 1 Aug 1997

Ohno H, Kaneko S, Kobayashi K, Murakami S

Abstract excerpt

Serum levels of interleukin-6 (IL-6) are elevated in acute and chronic hepatitis B patients. The effect of IL-6 and its transcription factor of NF-IL6 (a nuclear factor for IL-6) on hepatitis B virus (HBV) enhancer 1 (Enh1), which controls HBV X expression, were investigated in HepG2 cells. Twenty ng/ml of IL-6 increased 4-fold the enhancer activity of Enh1 according to the CAT assay. The IL-6 stimulation was...

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Identifiers

PMID: 9260690
DOI: 10.1002/(sici)1096-9071(199708)52:4<413::aid-jmv12>3.0.co;2-h

Genes

CAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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