Article
HNF3 binds and activates the second enhancer, ENII, of hepatitis B virus.
Virology - 20 Dec 1995
Li M, Xie Y, Wu X, Kong Y, Wang Y
Abstract excerpt
The basic functional unit of hepatitus B virus (HBV) enhancer II (ENII) is located within nt 1687-1774, which is defined as the B fragment in our previous papers. A major trans-acting factor binding site has been identified within the B fragment. The sequence corresponding to this binding site wa...
Topics
- Base Sequence
- Binding Sites
- DNA, Viral
- DNA-Binding Proteins
- Enhancer Elements, Genetic
- HeLa Cells
- Hepatitis B virus
- Hepatocyte Nuclear Factor 3-alpha
- Hepatocyte Nuclear Factor 3-beta
- Humans
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Protein Binding
- Structure-Activity Relationship
- Transcription Factors
- Tumor Cells, Cultured