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Article

Enhancer I Predominance in Hepatitis B Virus Gene Expression

28 Jan 2004

Abstract excerpt

Previous studies of human hepatitis B virus (HBV) transcription revealed the requirement of two enhancer elements. Enhancer I (EnhI) is located upstream of the X promoter and is targeted by multiple activators, including basic leucine zipper proteins, and enhancer II (EnhII) is located upstream to the PreCore promoter and is targeted mainly by nuclear receptors (NRs). The mode of interplay between these enhancers...

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PMID: 14749394
DOI: 10.1128/mcb.24.4.1799-1808.2004

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