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Article

Susceptibility to Mycobacterium tuberculosis infection in HIV-positive patients is associated with CARD8 genetic variant.

Journal of acquired immune deficiency syndromes (1999) - 1 Jun 2013

Pontillo Alessandra, Carvalho Marcia S, Kamada Anselmo J, Moura Ronald, Schindler Haiana C, Duarte Alberto J S, Crovella Sergio

Abstract excerpt

HLA and other genetic variants, playing an important role in innate and adaptive immunity, are known to influence tuberculosis (TB) development in HIV-1-positive (HIV+) patients. Because inflammasome genes contribute to HIV-1 susceptibility, we investigated the possible association between polymo...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23507658
DOI: 10.1097/QAI.0b013e31828f93bb

Genes

CARD8
AIM2
CASP1
NLRP1
NLRP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23507658-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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