Branched-chain fatty acids produced by mutants of Streptomyces fradiae, putative precursors of the lactone ring of tylosin.

doi:10.1128/AAC.34.8.1535

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Article

Branched-chain fatty acids produced by mutants of Streptomyces fradiae, putative precursors of the lactone ring of tylosin.

Antimicrobial agents and chemotherapy - 1 Aug 1990

Huber M L, Paschal J W, Leeds J P, Kirst H A, Wind J A, Miller F D, Turner J R

Abstract excerpt

Three branched-chain fatty acids (7-hydroxy-4,6-dimethylnona-2,4-dienoic acid [compound 1], its 7-epimer [compound 2], and 7-keto-4,6-dimethylnona-2,4-dienoic acid [compound 3]) and a ketone (9-hydroxy-6,8-dimethylundeca-4,6-dien-3-one [compound 4]) were isolated from the culture broth of mutants...

Topics

Alcohols
Cerulenin
Chromatography, High Pressure Liquid
Culture Media
Fatty Acids
Ketones
Lactones
Magnetic Resonance Spectroscopy
Mutation
Phenotype
Streptomyces
Tylosin

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