Article
Synthesis of hydrolytic enzymes during production of tylosin by Streptomyces fradiae.
Journal of industrial microbiology - 1 Jul 1992
Brahimi-Horn M C, Luo S H, Wang S L, Gau S W, Mou D G
Abstract excerpt
The exposure of a wild-type tylosin producing strain of Streptomyces fradiae to mutagenic agents resulted in the isolation of several tylosin over-producing strains. Examination of three mutants, T4310, 612 and 3204 showed that improved tylosin production was associated with increased hydrolytic enzyme activity and cell growth. The wild-type strain showed lower levels of hydrolytic activity including, protease,...
Topics
- Amylases
- Endopeptidases
- Esterases
- Fermentation
- Kinetics
- Lipase
- Mutation
- Streptomyces
- Tylosin