Article
The mycarose-biosynthetic genes of Streptomyces fradiae, producer of tylosin The GenBank accession number for the sequence determined in this work is AF147704.
1 Jan 2000
Abstract excerpt
The tylCK region of the Streptomyces fradiae genome was sequenced, revealing an incomplete set of five tylC genes encoding all-but-one of the enzymes involved in the biosynthesis of mycarose. The latter is a 6-deoxyhexose sugar required during production of the macrolide antibiotic, tylosin. The missing mycarose-biosynthetic gene, tylCVI, was found about 50 kb distant from its functional partners, on the other...
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