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Article

Identification of novel tylosin analogues generated by a wblA disruption mutant of Streptomyces ansochromogenes.

Microbial cell factories - 2 Nov 2015

Lu Cheng, Liao Guojian, Zhang Jihui, Tan Huarong

Abstract excerpt

BACKGROUND: Streptomyces, as the main source of antibiotics, has been intensively exploited for discovering new drug candidates to combat the evolving pathogens. Disruption of wblA, an actinobacteria-specific gene controlling major developmental transition, can cause the alteration of phenotype and morphology in many species of Streptomyces. One wblA homologue was found in Streptomyces ansochromogenes 7100 by...

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Identifiers

PMID: 26525981
DOI: 10.1186/s12934-015-0359-5
PMCID: PMC4630966

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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