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Article

Identification and Validation of Putative Nesprin Variants.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2016

Autore Flavia, Shanahan Catherine M, Zhang Qiuping

Abstract excerpt

Nesprins are a family of multi-isomeric scaffolding proteins that were originally identified at the nuclear envelope (NE), where they bind to lamin A/C, emerin, and SUN-domain containing proteins, to form the LInker of Nucleoskeleton-and-Cytoskeleton (LINC) complex that connects the NE to the actin cytoskeleton. However, nesprin genes also give rise to a variety of tissue-specific variants of different sizes with...

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PMID: 27147044
DOI: 10.1007/978-1-4939-3530-7_13

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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