Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of Bcl-2 rs956572 SNP on regional gray matter volumes and cognitive function in elderly males without dementia.

Age (Dordrecht, Netherlands) - 1 Apr 2013

Liu Mu-En, Huang Chu-Chung, Hwang Jen-Ping, Yang Albert C, Tu Pei-Chi, Yeh Heng-Liang, Hong Chen-Jee, Liou Ying-Jay, Chen Jin-Fan, Lin Ching-Po, Tsai Shih-Jen

Abstract excerpt

The Bcl-2 gene is a major regulator of neural plasticity and cellular resilience. A single-nucleotide polymorphism (SNP) in the Bcl-2 gene, Bcl-2 rs956572, significantly modulates the expression of Bcl-2 protein and cellular vulnerability to apoptosis. This study investigated the association between the Bcl-2 rs956572 SNP and brain structural abnormalities in non-demented elders, and to test the relationship...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chi-Square Distribution
Share to Cognition Disorders
Share to Genes, bcl-2
Share to Image Interpretation, Computer-Assisted
Share to Language Disorders
Share to Neuropsychological Tests
Share to Taiwan
Share to Temporal Lobe

Source

Open in PubMed Open full text

Identifiers

PMID: 22198673
DOI: 10.1007/s11357-011-9367-5
PMCID: PMC3592959

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of Bcl-2 rs956572 SNP on regional gray matter volumes and cognitive function in elderly males without dementia.PMID 22198673Read ↗

Bcl-2 polymorphism influences gray matter volume in the ventral striatum in healthy humans.Semantic proximity Read ↗

Associations of Bcl-2 rs956572 genotype groups in the structural covariance network in early-stage Alzheimer's disease.Semantic proximity Read ↗

Cognitive reserve and TMEM106B genotype modulate brain damage in presymptomatic frontotemporal dementia: a GENFI study.Semantic proximity Read ↗

Mendelian randomization in Alzheimer’s disease and mild cognitive impairment: Hippocampal volume associationsSemantic proximity Read ↗

A TREML2 missense variant influences specific hippocampal subfield volumes in cognitively normal elderly subjects.Semantic proximity Read ↗

Effect of the BDNF Val66Met polymorphism on regional gray matter volumes and cognitive function in the Chinese population.Semantic proximity Read ↗

Effects of HLA-DRB1/DQB1 Genetic Variants on Neuroimaging in Healthy, Mild Cognitive Impairment, and Alzheimer's Disease Cohorts.Semantic proximity Read ↗

Influence of BDNF rs10835210 on right parahippocampal volume and its related cognitive function in first- and multiple-episode bipolar disorder.Semantic proximity Read ↗

Functional impact of a recently identified quantitative trait locus for hippocampal volume with genome-wide support.Semantic proximity Read ↗

Genetically-mediated Grey and White Matter Alteration in Normal Elderly Individuals with the CLU-C Allele Gene.Semantic proximity Read ↗

Reduced hippocampus volume and memory performance in bipolar disorder patients carrying the BDNF val66met met allele.Semantic proximity Read ↗

Viral hepatitis moderates the impact of TGFB1 on neurocognitive impairment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.