Article
Evolution of precore/core promoter mutations in hepatitis B carriers with hepatitis B e antigen seroreversion.
Journal of medical virology - 1 Oct 2004
Liu Chun-Jen, Chen Pei-Jer, Lai Ming-Yang, Kao Jia-Horng, Chen Ding-Shinn
Abstract excerpt
The evolution of precore stop codon mutation (A1896) and dinucleotide mutation (T1762/A1764) in the basic core promoter (BCP) of hepatitis B virus (HBV) genome during transient seroconversion and seroreversion of hepatitis B e antigen (HBeAg) remains unclarified. Five HBeAg-positive HBV carriers who experienced transient seroconversion followed by seroreversion of HBeAg (Group I, 3.3%) and 3 HBeAg-negative HBV...
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