Article
Prevalence and impact of minority variant drug resistance mutations in primary HIV-1 infection.
PloS one - 1 Jan 2011
Stekler Joanne D, Ellis Giovanina M, Carlsson Jacquelyn, Eilers Braiden, Holte Sarah, Maenza Janine, Stevens Claire E, Collier Ann C, Frenkel Lisa M
Abstract excerpt
OBJECTIVE: To evaluate minority variant drug resistance mutations detected by the oligonucleotide ligation assay (OLA) but not consensus sequencing among subjects with primary HIV-1 infection. DESIGN/METHODS: Observational, longitudinal cohort study. Consensus sequencing and OLA were performed on the first available specimens from 99 subjects enrolled after 1996. Survival analyses, adjusted for HIV-1 RNA levels...
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