Article
Pre-treatment minority HIV-1 drug resistance mutations and long term virological outcomes: is prediction possible?
Virology journal - 12 Oct 2016
Mzingwane M L, Tiemessen C T, Richter K L, Mayaphi S H, Hunt G, Bowyer S M
Abstract excerpt
BACKGROUND: Although the use of highly active antiretroviral therapy in HIV positive individuals has proved to be effective in suppressing the virus to below detection limits of commonly used assays, virological failure associated with drug resistance is still a major challenge in some settings. The prevalence and effect of pre-treatment resistance associated variants on virological outcomes may also be...
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