Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Target site recognition by a diversity-generating retroelement.

PLoS genetics - 1 Dec 2011

Guo Huatao, Tse Longping V, Nieh Angela W, Czornyj Elizabeth, Williams Steven, Oukil Sabrina, Liu Vincent B, Miller Jeff F

Abstract excerpt

Diversity-generating retroelements (DGRs) are in vivo sequence diversification machines that are widely distributed in bacterial, phage, and plasmid genomes. They function to introduce vast amounts of targeted diversity into protein-encoding DNA sequences via mutagenic homing. Adenine residues are converted to random nucleotides in a retrotransposition process from a donor template repeat (TR) to a recipient...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteriophages
Share to Base Sequence
Share to DNA, Complementary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inverted Repeat Sequences

Share to Open Reading Frames

Share to Proteins

Share to Retroelements

Share to Structure-Activity Relationship

Source

Open in PubMed Open full text

Identifiers

PMID: 22194701
DOI: 10.1371/journal.pgen.1002414
PMCID: PMC3240598

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Target site recognition by a diversity-generating retroelement.PMID 22194701Read ↗

Diversity-generating Retroelements in Phage and Bacterial Genomes.Semantic proximity Read ↗

Diversity-generating retroelement homing regenerates target sequences for repeated rounds of codon rewriting and protein diversification.Semantic proximity Read ↗

High-throughput analyses of a reconstituted diversity-generating retroelement identify intrinsic and extrinsic determinants of diversification.Semantic proximity Read ↗

Tropism switching in Bordetella bacteriophage defines a family of diversity-generating retroelements.Semantic proximity Read ↗

DGR mutagenic transposition occurs via hypermutagenic reverse transcription primed by nicked template RNA.Semantic proximity Read ↗

Accelerated Evolution by Diversity-Generating Retroelements.Semantic proximity Read ↗

Template-assisted synthesis of adenine-mutagenized cDNA by a retroelement protein complex.Semantic proximity Read ↗

Determinants of Adenine-mutagenesis in Diversity-Generating RetroelementsSemantic proximity Read ↗

A diversity-generating retroelement encoded by a globally ubiquitous Bacteroides phageSemantic proximity Read ↗

Diversity-generating retroelements: natural variation, classification and evolution inferred from a large-scale genomic survey.Semantic proximity Read ↗

Analysis of a comprehensive dataset of diversity generating retroelements generated by the program DiGReF.Semantic proximity Read ↗

Lineage-Specific Evolution, Structural Diversity, and Activity of R2 Retrotransposons in AnimalsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.