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Article

Diversity-generating retroelements: natural variation, classification and evolution inferred from a large-scale genomic survey.

Nucleic acids research - 9 Jan 2018

Wu Li, Gingery Mari, Abebe Michael, Arambula Diego, Czornyj Elizabeth, Handa Sumit, Khan Hamza, Liu Minghsun, Pohlschroder Mechthild, Shaw Kharissa L, Du Amy, Guo Huatao, Ghosh Partho, Miller Jeff F, Zimmerly Steven

Abstract excerpt

Diversity-generating retroelements (DGRs) are novel genetic elements that use reverse transcription to generate vast numbers of sequence variants in specific target genes. Here, we present a detailed comparative bioinformatic analysis that depicts the landscape of DGR sequences in nature as represented by data in GenBank. Over 350 unique DGRs are identified, which together form a curated reference set of...

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Identifiers

PMID: 29186518
DOI: 10.1093/nar/gkx1150
PMCID: PMC5758913

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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