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Article

Impact of CYP2C19 gene polymorphisms on warfarin dose requirement: a systematic review and meta-analysis.

Pharmacogenomics - 1 Nov 2022

Wang Dongxu, Yong Ling, Zhang Qing, Chen Hao

Abstract excerpt

Background: Various genetic factors influence warfarin maintenance dose. Methods: A literature search was performed on PubMed, Embase and the Cochrane Library, and a meta-analysis to analyze the impact of CYP2C19 polymorphisms on warfarin maintenance dose was conducted. Results: From nine studies encompassing 1393 patients, three CYP2C19 SNPs were identified: rs4244285, rs4986893 and rs3814637. Warfarin...

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Identifiers

PMID: 36222113
DOI: 10.2217/pgs-2022-0106

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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