Article
The impact of genetic polymorphisms and patient characteristics on warfarin dose requirements: a cross-sectional study in Iran.
Clinical therapeutics - 1 Jun 2010
Namazi Soha, Azarpira Negar, Hendijani Fatemeh, Khorshid Maryam Banan, Vessal Ghazal, Mehdipour Ahmad Reza
Abstract excerpt
BACKGROUND: Warfarin is the most commonly prescribed oral anticoagulant drug for prophylaxis and treatment of venous and arterial thromboembolic disorders. Its anticoagulant effect is widely variable between patients because of pharmacodynamic, pharmacokinetic, and pharmacogenetic factors. OBJECTIVE: This study was conducted to identify the associations between demographic characteristics, warfarin maintenance...
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