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Article

Influence of CYP2C9 genotype on warfarin dose requirements--a systematic review and meta-analysis.

European journal of clinical pharmacology - 1 Apr 2009

Lindh Jonatan D, Holm Lennart, Andersson Marine L, Rane Anders

Abstract excerpt

PURPOSE: To quantify the influence of common cytochrome P450 2C9 (CYP2C9) polymorphisms on warfarin dose requirements. METHODS: A systematic review and a meta-analysis, calculating the warfarin dose reduction associated with the five most common variant CYP2C9 genotypes. RESULTS: Thirty-nine studies (7,907 patients) were included in the meta-analysis. Compared to the CYP2C9*1/*1 genotype, the CYP2C9*1/*2,...

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Source

Identifiers

PMID: 19031075
DOI: 10.1007/s00228-008-0584-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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