Article
Prevalence of apolipoprotein E4 genotype and homozygotes (APOE e4/4) among patients diagnosed with Alzheimer's disease: a systematic review and meta-analysis.
Neuroepidemiology - 1 Jan 2012
Ward Alex, Crean Sheila, Mercaldi Catherine J, Collins Jenna M, Boyd Dylan, Cook Michael N, Arrighi H Michael
Abstract excerpt
BACKGROUND: Population allele frequencies of apolipoprotein E (APOE) vary by geographic region. The purpose of this study is to summarize and evaluate published estimates for the prevalence of APOE e4 carrier status among the population diagnosed with Alzheimer's disease (AD) by geographic region and country. METHODS: A systematic review of English-language publications from January 1, 1985, through May 31, 2010,...
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