Article
Apolipoprotein E in Alzheimer's disease risk and case detection: a case-control study.
Journal of clinical epidemiology - 1 Oct 1996
Kukull W A, Schellenberg G D, Bowen J D, McCormick W C, Yu C E, Teri L, Thompson J D, O'Meara E S, Larson E B
Abstract excerpt
The objective of this study was to describe the association between the epsilon 4 allele of the apolipoprotein E gene (APOE E4) and Alzheimer's disease (AD) and to evaluate APOE E4 genotyping as a test for AD. The study base of this case-control study included about 23,000 persons 60 year of age or greater (a large health maintenance organization); the demographic characteristics of this group are similar to...
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