Article
Role of CYP1B1 gene polymorphisms in bladder cancer susceptibility.
The Journal of urology - 1 Feb 2012
Salinas-Sánchez Antonio S, Donate-Moreno María J, López-Garrido María-Pilar, Giménez-Bachs José M, Escribano Julio
Abstract excerpt
PURPOSE: CYP1B1 activates procarcinogens in some human tissues, including the urinary tract. Changes related to genetic polymorphisms are a known risk factor for cancer. We analyzed the association between CYP1B1 sequence variations and bladder cancer. MATERIALS AND METHODS: Sequence variations in the coding region (exons 2 and 3) and the neighboring introns of CYP1B1 were analyzed by direct polymerase chain...
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