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Article

Association of CYP1B1 L432V polymorphism with urinary cancer susceptibility: a meta-analysis.

Diagnostic pathology - 9 Jun 2014

Jiang Weifan, Sun Guang, Xiong Jianhua, Xi Xiaoqing, Shi Zimin

Abstract excerpt

BACKGROUND: The Cytochrome P450 1B1 (CYP1B1) is a key P450 enzyme involved in the metabolism of exogenous and endogenous substrates. Previous studies have reported the existence of CYP1B1 L432V missense polymorphism in prostate, bladder and renal cancers. However, the effects of this polymorphism on the risk of these cancers remain conflicting. Therefore, we performed a meta-analysis to assess the association...

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Identifiers

PMID: 24913727
DOI: 10.1186/1746-1596-9-113
PMCID: PMC4067118

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