Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Three polymorphisms in cytochrome P450 1B1 (CYP1B1) gene and breast cancer risk: a meta-analysis.

Breast cancer research and treatment - 1 Jul 2010

Economopoulos Konstantinos P, Sergentanis Theodoros N

Abstract excerpt

Cytochrome P450 1B1 (CYP1B1) is a P450 enzyme implicated in the metabolism of exogenous and endogenous substrates. The metabolism of polycyclic aromatic hydrocarbons and other procarcinogens through CYP1B1 may well lead to their activation. Apart from the extensively studied Val432Leu polymorphism, three single nucleotide polymorphisms in CYP1B1 have been studied concerning their potential implication in terms of...

Topics

Join the communities discussing this publication.

Aryl Hydrocarbon Hydroxylases
Breast Neoplasms
Cytochrome P-450 CYP1B1
Cytochrome P-450 Enzyme System
Heterozygote

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Risk Assessment

Source

Identifiers

PMID: 20054638
DOI: 10.1007/s10549-009-0728-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Three polymorphisms in cytochrome P450 1B1 (CYP1B1) gene and breast cancer risk: a meta-analysis.PMID 20054638Read ↗

Four polymorphisms in cytochrome P450 1A1 (CYP1A1) gene and breast cancer risk: a meta-analysis.Semantic proximity Read ↗

Cytochrome P1B1 (CYP1B1) polymorphisms and cancer risk: a meta-analysis of 52 studies.Semantic proximity Read ↗

Cytochrome P1B1 (CYP1B1) polymorphisms and ovarian cancer risk: a meta-analysis.Semantic proximity Read ↗

Cytochrome P-450 1A1 gene polymorphisms and risk of breast cancer: a HuGE review.Semantic proximity Read ↗

Cytochrome P450 1B1 and catechol-O-methyltransferase genetic polymorphisms and breast cancer risk in Chinese women: results from the shanghai breast cancer study and a meta-analysis.Semantic proximity Read ↗

Association between the CYP1B1 polymorphisms and risk of cancer: a meta-analysis.Semantic proximity Read ↗

No association between CYP1B1 Val432Leu polymorphism and breast cancer risk: a meta-analysis involving 40,303 subjects.Semantic proximity Read ↗

Cytochrome P450 1A1 (CYP1A1) Gene Polymorphisms and Susceptibility to Breast Cancer: a Meta-Analysis in the Chinese Population.Semantic proximity Read ↗

Association between CYP1A2 and CYP1B1 polymorphisms and colorectal cancer risk: a meta-analysis.Semantic proximity Read ↗

CYP1A1 and GSTP1 gene variations in breast cancer: a systematic review and case-control study.Semantic proximity Read ↗

Association of CYP1B1 genetic polymorphism with incidence to breast and lung cancer.Semantic proximity Read ↗

CYP1B1 and predisposition to breast cancer in Poland.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.