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Article

The CYP1B1 Leu432Val polymorphism and risk of urinary system cancers.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 May 2014

Liu Yi, Lin Chang-sheng, Zhang Ai-min, Song Hua, Fan Chang-chun

Abstract excerpt

The cytochrome P450 1B1 (CYP1B1) gene plays a key role in the metabolism of various carcinogens. The CYP1B1 Leu432Val polymorphism leads to leucine to valine substitution at codon 432. A lot of studies have shown that the CYP1B1 Leu432Val polymorphism was associated with urinary system cancers, especially prostate cancer. However, the results were still inconclusive. In this meta-analysis, by searching online...

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Share to Aryl Hydrocarbon Hydroxylases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Genetic

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Identifiers

PMID: 24453031
DOI: 10.1007/s13277-014-1617-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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The CYP1B1 Leu432Val polymorphism and risk of urinary system cancers.PMID 24453031Read ↗

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Prostate cancer risk and aggressiveness associated with the CYP1B1 4326C/G (Leu432Val) polymorphism: a meta-analysis of 2788 cases and 2968 controls.Semantic proximity Read ↗

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