Article
Association of complement C3 gene variants with renal transplant outcome of deceased cardiac dead donor kidneys.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Mar 2012
Damman J, Daha M R, Leuvenink H G, van Goor H, Hillebrands J L, Dijk M C van, Hepkema B G, Snieder H, Born J van den, de Borst M H, Bakker S J, Navis G J, Ploeg R J, Seelen M A
Abstract excerpt
Local renal complement activation by the donor kidney plays an important role in the pathogenesis of renal injury inherent to kidney transplantation. Contradictory results were reported about the protective effects of the donor C3F allotype on renal allograft outcome. We investigated the influence of the donor C3F allotype on renal transplant outcome, taking all different donor types into account. C3 allotypes of...
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