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Article

C3 polymorphisms and allograft outcome in renal transplantation.

The New England journal of medicine - 26 Feb 2009

Varagunam Mira, Yaqoob Muhammad M, Döhler Bernd, Opelz Gerhard

Abstract excerpt

BACKGROUND: Complement activation plays a role in the development of chronic allograft nephropathy, a common cause of late allograft loss. The role of two complement component 3 (C3) allotypes, called C3F (fast) and C3S (slow) on the basis of their electrophoretic motility, in the long-term outcome of renal allografts remains controversial. METHODS: We selected a random sample of 1147 donor and recipient pairs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19246358
DOI: 10.1056/NEJMoa0801861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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