Article
Complement component C3 allotypes and outcomes in liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society - 1 Feb 2010
Dhillon Navdeep, Walsh Liron, Krüger Bernd, Mehrotra Anita, Ward Stephen C, Godbold Jim, Radwan Mohamed, Schiano Thomas, Murphy Barbara, Schröppel Bernd
Abstract excerpt
The complement system has been implicated in the pathogenesis of liver diseases. Human complement component C3 (C3) exists as 2 allotypes, fast (F) and slow (S). We conducted a study to address the influence of these alleles on ischemia-reperfusion (IR) injury and graft survival in liver transplant recipients. Four hundred thirty patients receiving liver transplants from 2000 to 2004 were included. C3 allotypes...
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