Article
Molecular analysis of C3 allotypes related to transplant outcome in human renal allografts.
Transplantation - 15 Dec 1995
Andrews P A, Finn J E, Mathieson P W, Sacks S H
Abstract excerpt
The third component of complement (C3) exists in two main allotypic forms, C3S and C3F, which can be distinguished at the molecular level using a variation of the polymerase chain reaction. An increased frequency of the C3F allele has been noted in a number of autoimmune and inflammatory conditions affecting the kidney, including systemic vasculitis, IgA nephropathy, and type II mesangiocapillary nephritis....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.