Article
Systematic assessment of the influence of complement gene polymorphisms on kidney transplant outcome.
Immunobiology - 1 Apr 2016
Ermini Luca, Weale Michael E, Brown Katherine M, Mesa Irene Rebollo, Howell W Martin, Vaughan Robert, Chowdhury Paramit, Sacks Steven H, Sheerin Neil S
Abstract excerpt
The importance of the innate immune system, including complement, in causing transplant injury and augmenting adaptive immune responses is increasingly recognized. Therefore variability in graft outcome may in part be due to genetic polymorphism in genes encoding proteins of the immune system. This study assessed the relationship between single nucleotide polymorphisms (SNPs) in complement genes and outcome after...
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