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Article

Lectin complement pathway gene profile of the donor and recipient does not influence graft outcome after kidney transplantation.

Molecular immunology - 1 Feb 2012

Damman Jeffrey, Kok Julian L, Snieder Harold, Leuvenink Henri G, van Goor Harry, Hillebrands Jan-Luuk, van Dijk Marcory C, Hepkema Bouke G, Reznichenko Anna, van den Born Jaap, de Borst Martin H, Bakker Stephan J, Navis Gerjan J, Ploeg Rutger J, Seelen Marc A

Abstract excerpt

In kidney transplantation, complement activation was found to be induced by donor brain death, renal ischemia-reperfusion injury and allograft rejection. There are three known pathways of complement activation: the classical, lectin and the alternative pathway. The lectin complement pathway can be activated upon pattern recognition by mannan binding lectin (MBL) or ficolins (FCN). Single nucleotide polymorphisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22173059
DOI: 10.1016/j.molimm.2011.11.009

Genes

FCN2
MBL2
MASP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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