Article
Polymorphisms in the lectin pathway of complement activation influence the incidence of acute rejection and graft outcome after kidney transplantation.
Kidney international - 1 Apr 2016
Golshayan Déla, Wójtowicz Agnieszka, Bibert Stéphanie, Pyndiah Nitisha, Manuel Oriol, Binet Isabelle, Buhler Leo H, Huynh-Do Uyen, Mueller Thomas, Steiger Jürg, Pascual Manuel, Meylan Pascal, Bochud Pierre-Yves
Abstract excerpt
There are conflicting data on the role of the lectin pathway of complement activation and its recognition molecules in acute rejection and outcome after transplantation. To help resolve this we analyzed polymorphisms and serum levels of lectin pathway components in 710 consecutive kidney transplant recipients enrolled in the nationwide Swiss Transplant Cohort Study, together with all biopsy-proven rejection...
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