Article
Validation of warfarin pharmacogenetic algorithms in clinical practice.
Pharmacogenomics - 1 Jan 2012
Marin-Leblanc Mélina, Perreault Sylvie, Bahroun Imen, Lapointe Mathieu, Mongrain Ian, Provost Sylvie, Turgeon Jacques, Talajic Mario, Brugada Ramon, Phillips Michael, Tardif Jean-Claude, Dubé Marie-Pierre
Abstract excerpt
AIM: The goal of this study was to evaluate the performance of four warfarin pharmacogenetic algorithms in a real clinical setting, namely the algorithms of Gage et al., Michaud et al., Wadelius et al. and the International Warfarin Pharmacogenetics Consortium algorithm. PATIENTS & METHODS: Data was obtained retrospectively for 605 patients who had initiated warfarin therapy at the Montreal Heart Institute....
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