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Article

A new warfarin dosing algorithm including VKORC1 3730 G > A polymorphism: comparison with results obtained by other published algorithms.

European journal of clinical pharmacology - 1 Aug 2012

Cini Michela, Legnani Cristina, Cosmi Benilde, Guazzaloca Giuliana, Valdrè Lelia, Frascaro Mirella, Palareti Gualtiero

Abstract excerpt

PURPOSE: Warfarin dosing is affected by clinical and genetic variants, but the contribution of the genotype associated with warfarin resistance in pharmacogenetic algorithms has not been well assessed yet. We developed a new dosing algorithm including polymorphisms associated both with warfarin sensitivity and resistance in the Italian population, and its performance was compared with those of eight previously...

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Source

Identifiers

PMID: 22349464
DOI: 10.1007/s00228-012-1226-5

Genes

VKORC1
OAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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