Article

Pharmacogenetics in warfarin therapy

2013-01-01

Abstract excerpt

Warfarin is a challenging drug to dose accurately, especially during the initiation phase because of its narrow therapeutic range and large inter-individual variability. Therefore, the aim of this thesis was to investigate the use of pharmacogenetics and clinical data to improve warfarin therapy. Genetic variants in cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1) are known to influence warfar...

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Literature Corpus work: 6cb0efb3-c227-552a-8021-d0e542c5e5c5
DOI: 10.17638/00018317

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