Article
Validation of warfarin pharmacogenetic algorithms in 586 Han Chinese patients.
Pharmacogenomics - 1 Jan 2015
Peng Qi, Huang Shujun, Chen Xiaoying, Yuan Yayan, Yu Yajun, Tao Liang, Zhang Zhenlu, Xu Mousheng
Abstract excerpt
AIM: To compare the accuracy of the nine selected algorithms for predicting warfarin dose with 586 Han Chinese patients. MATERIALS & METHODS: Genotyping of VKORC1 1639G>A, CYP2C9*2 and CYP2C9*3 variants was performed. Both the mean absolute error and ideal estimation value were used for comparison. RESULTS: The top three performers were from East Asians. The algorithms from Caucasians generally performed better...
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