Article
Validation of pharmacogenetic algorithms and warfarin dosing table in Egyptian patients.
International journal of clinical pharmacy - 1 Dec 2012
Bazan Naglaa Samir, Sabry Nirmeen Ahmed, Rizk Amal, Mokhtar Sherif, Badary Osama
Abstract excerpt
BACKGROUND: Warfarin remains a difficult drug to use due to the large variability in dose response. Clear understanding of the accuracy of warfarin pharmacogenetic dosing methods might lead to appropriate control of anticoagulation. OBJECTIVE: This study aims to evaluate the accuracy of warfarin dosing table and two pharmacogenetic algorithms, namely the algorithms of Gage et al. (Clin Pharmacol Ther 84:326-331,...
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