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Article

Estimation of the warfarin dose with clinical and pharmacogenetic data.

The New England journal of medicine - 19 Feb 2009

Klein T E, Altman R B, Eriksson N, Gage B F, Kimmel S E, Lee M-T M, Limdi N A, Page D, Roden D M, Wagner M J, Caldwell M D, Johnson J A

Abstract excerpt

BACKGROUND: Genetic variability among patients plays an important role in determining the dose of warfarin that should be used when oral anticoagulation is initiated, but practical methods of using genetic information have not been evaluated in a diverse and large population. We developed and used an algorithm for estimating the appropriate warfarin dose that is based on both clinical and genetic data from a...

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Identifiers

PMID: 19228618
DOI: 10.1056/NEJMoa0809329
PMCID: PMC2722908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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